Photodynamic inactivation of bacteriophage and its inhibition.
نویسنده
چکیده
The photosensitizing action of dyes on biological systems is commonly designated as "photodynamic action." The subject has been well summarized in a monograph by Blum (1941). Earlier studies on photodynamic inactivation of bacteriophages were made by Clifton (1931), and by Perdrau and Todd (1933). Burnet (1933) discovered that the relative sensitivities of phage strains to photodynamic inactivation could be correlated with serological groupings, and hence was of taxonomic significance. Quantitative studies of the kinetics of photodynamic inactivation of bacteriophages by Welsh and Adams (1954) confirmed Burnet's conclusions. The experiments undertaken in the present study were designed to find the conditions necessary for the photodynamic inactivation of bacteriophages. A mechanism for the inactivation or its inhibition in the T-series of coliphages will be described.
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 75 4 شماره
صفحات -
تاریخ انتشار 1958